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RAG vs Fine-Tuning: When to Use Each

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RAG vs Fine-Tuning: When to Use Each
RAG vs Fine-Tuning: Side-by-side comparison of RAG pipeline vs fine-tuning pipeline
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UIT University 365 Institute of Technology

Series AI Engineering | Level Basic (Free)

Duration 15 to 20 minutes | Access Free

IT Engineering, AI and Applied AI, Data Science, Software Development, Digital Transformation


UNOP isochrone

UNOP Sound (University 365 Neuroscience Oriented Pedagogy)

Take five minutes to prepare your brain. Play the isochronous tone track (40Hz gamma frequency) with your eyes closed. Gamma-frequency tones before a learning session raise attention and make the material easier to absorb.

[Audio player: UNOP Pre-Lecture Isochrone (40Hz, 5 minutes)]

Table of Contents




The Hook: Your Question, Answered


Your team needs a chatbot that answers customer questions using your company documentation. Someone says "let's fine-tune GPT on our docs." Someone else says "we should use RAG." Who is right?


In 2026, the answer is almost always: start with RAG, then add fine-tuning only for the specific behaviors RAG cannot fix. Fine-tuning teaches a model how to behave. RAG gives a model the facts it needs. Most teams confuse the two and fine-tune when they should retrieve.


The most common mistake in LLM application development is using fine-tuning to teach facts. Fine-tuned models go stale the moment your data changes. RAG systems update by replacing documents, no retraining required.


In the next 20 minutes, you will understand exactly when to use each approach, when to combine them, and when to use neither.


Side-by-side comparison of RAG pipeline vs fine-tuning pipeline
Side-by-side comparison of RAG pipeline vs fine-tuning pipeline


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What Is RAG? Retrieval Augmented Generation Explained


RAG connects a language model to an external knowledge source at inference time. The model stays unchanged. Instead of baking knowledge into model weights, you store documents in a searchable index and retrieve relevant chunks at query time.


The RAG Pipeline


A modern RAG pipeline has four stages:


1. Indexing: Documents are chunked into passages (typically 400 to 600 tokens), embedded into vector representations, and stored in a vector database. Modern systems also index for keyword search (BM25) alongside vector search.


2. Retrieval: A user query is embedded and matched against the index. Hybrid retrieval combines dense vector similarity and sparse keyword matching to find the most relevant passages.


3. Re-ranking: A cross-encoder re-ranker (such as Cohere Rerank or BGE Reranker) re-orders the top 20 to 50 candidates by true relevance to the query. This is the single biggest quality lever in RAG, and the step most teams skip.


4. Generation: The top-ranked passages are inserted into the LLM prompt as context. The model generates an answer grounded in those passages, often with citations.


Why RAG Works


- Updates are instant: Replace a document in the index and the next query uses the new content. No retraining cycle.


- Sources are traceable: Every answer points to the specific passages that grounded it. This matters for compliance, audits, and user trust.


- Models are swappable: Move from GPT to Claude to Llama without redoing your retrieval pipeline. The knowledge lives in the index, not the weights.


- Cost is predictable: You pay for embedding API calls and vector database storage. No GPU training costs.


What Is RAG? Retrieval Augmented Generation Explained
What Is RAG? Retrieval Augmented Generation Explained: pedagogical overview


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What Is Fine-Tuning? Adapting Model Weights


Fine-tuning modifies the model itself. You train the model on examples of inputs and desired outputs, adjusting its internal weights to produce responses that match your training data. The new behavior is baked into the model.


Types of Fine-Tuning


Full fine-tuning updates all model parameters. It requires significant compute (multiple GPUs, hours to days of training) and produces a large artifact. It is the most powerful form of fine-tuning but the hardest to maintain and roll back.


LoRA (Low-Rank Adaptation) trains a small adapter module (often less than 1% of model parameters) that sits on top of the frozen base model. LoRA is cheap, fast, reversible, and stackable. You can train multiple LoRA adapters for different tasks and swap them at inference time. For most fine-tuning use cases in 2026, LoRA is the right tool.


QLoRA extends LoRA with 4-bit quantization of the base model, reducing memory requirements further. This lets you fine-tune a 70B model on a single consumer GPU.


DPO (Direct Preference Optimization) and its variants (KTO, ORPO) have largely replaced classic RLHF in 2026. Instead of training a separate reward model and running PPO, you train directly on preference data: pairs of outputs where one is labeled better than the other. DPO is simpler, cheaper, and more stable than RLHF.


What Fine-Tuning Changes


Fine-tuning changes how the model behaves, not what it knows. A fine-tuned model produces outputs in the style, format, or tone of your training data. It does not learn new facts from fine-tuning data. If you fine-tune on your product documentation, the model may memorize some of it, but this knowledge goes stale the moment the documentation updates.


Comparison of full fine-tuning, LoRA, QLoRA, and DPO
Comparison of full fine-tuning, LoRA, QLoRA, and DPO


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The Core Difference: Knowledge vs Behavior


This is the single most important distinction in this lecture. Get this right and you will avoid the most expensive mistake in LLM development.


RAG Handles Knowledge


Use RAG when the model needs information it did not see during training: your product catalog, internal policies, customer history, legal documents, real-time data. RAG retrieves the facts at query time, so the model always answers from current data.


Fine-Tuning Handles Behavior


Use fine-tuning when the model has the right facts but produces them in the wrong way: wrong tone, wrong format, wrong structure, wrong language register. Fine-tuning teaches the model to consistently produce outputs that match your desired style.


The Rule


RAG for facts. Fine-tuning for behavior. If you need the model to know something, retrieve it. If you need the model to do something differently, fine-tune it.


Teams that fine-tune to teach facts end up with models that are expensive to train, expensive to maintain, and stale the moment the data changes. Teams that use RAG for everything end up with systems that cannot hold a consistent tone or format. The best systems use both, each for what it does best.


RAG vs Fine-Tuning core decision diagram v3
Decision diagram showing RAG for knowledge and fine-tuning for behavior


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When to Choose RAG: Five Scenarios


Scenario 1: Dynamic Knowledge


Your knowledge base changes frequently. Product prices update weekly. Policies change monthly. Support tickets arrive daily. Fine-tuning cannot keep up because each update requires a new training cycle. RAG updates by replacing documents in the index, which takes minutes.


Scenario 2: Source Citation Required


You need to show users or auditors where the answer came from. Fine-tuned models cannot point to a source document. RAG retrieves specific passages and can cite them directly. This is critical for legal, medical, financial, and compliance applications.


Scenario 3: Large Knowledge Base


Your corpus is larger than the model context window. Even with 1M-token windows, a large enterprise documentation set exceeds what fits in a single prompt. RAG retrieves only the relevant chunks, keeping the prompt size manageable.


Scenario 4: Multiple Knowledge Sources


You need to answer questions that span multiple data sources: internal docs, external APIs, databases, web pages. RAG can query multiple indices and combine results. Fine-tuning bakes one dataset into the weights and cannot mix sources at query time.


Scenario 5: Rapid Prototyping


You need a working system in days, not weeks. RAG pipelines can be built with off-the-shelf components (embedding model, vector database, LLM) in a few days. Fine-tuning requires data preparation, GPU provisioning, training, evaluation, and iteration cycles that take weeks.


Five scenarios where RAG is the right choice
Five scenarios where RAG is the right choice


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When to Choose Fine-Tuning: Three Scenarios


Scenario 1: Style, Tone, and Format Consistency


Your model gets the facts right (from RAG or from its training data) but produces outputs in the wrong style. It sounds too generic when it should sound like your brand. It writes paragraphs when you need structured JSON. It uses casual language when you need formal clinical language. A few hundred to a few thousand curated examples in a LoRA adapter lock in the desired behavior.


Scenario 2: Distillation for Cost and Latency


A frontier model (GPT-5, Claude Sonnet) can already do your task well with the right prompt, but the API cost at production volume is too high. You fine-tune a small open-source model (7B to 13B parameters) on the frontier model outputs for your specific task. The tuned small model delivers near-frontier quality at roughly one-tenth the inference cost and a fraction of the latency. This is the strongest commercial case for fine-tuning in 2026.


Scenario 3: Specialized Domain Reasoning


Your task requires domain-specific reasoning that the base model does not handle well out of the box. Examples include medical report structuring, legal contract clause extraction, or financial document analysis. Fine-tuning on domain examples teaches the model the reasoning patterns specific to your field. Pair this with RAG for the actual facts, and you get both specialized reasoning and current knowledge.



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The Hybrid Pattern: Best of Both Worlds


Most production systems that work well in 2026 use a hybrid approach. The pattern is straightforward:


Step 1: Build RAG First


Start with RAG. Prove the use case. Measure quality with an evaluation set. Collect data on where the system fails. This phase typically takes 1 to 3 weeks.


Step 2: Identify Residual Failures


After RAG is working, identify the failure modes that retrieval cannot fix: inconsistent formatting, wrong tone, JSON schema violations, domain reasoning gaps. These are behavioral problems, not knowledge problems.


Step 3: Fine-Tune for the Residuals


Fine-tune a smaller, cheaper base model to handle the behavioral residuals. Train a LoRA adapter on examples of the desired output format, tone, or reasoning pattern. Run the fine-tuned model inside the same RAG pipeline.


Step 4: Maintain Both Layers


The RAG layer handles knowledge updates by replacing documents. The fine-tuned adapter handles behavior. When a new base model comes out, you can retrain the adapter on the new base with a fraction of the original effort, and the RAG pipeline stays unchanged because it is model-agnostic.


This hybrid pattern stacks the strengths: live facts from retrieval, locked behavior from fine-tuning, lower inference cost than a frontier model alone.


The Hybrid Pattern: Best of Both Worlds
The Hybrid Pattern: Best of Both Worlds: pedagogical overview


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Cost, Latency, and Maintenance Compared


Dimension

RAG

Fine-Tuning (LoRA)

Hybrid

Initial setup time

1 to 3 weeks

4 to 8 weeks

6 to 12 weeks

Knowledge updates

Minutes (replace documents)

Days to weeks (retrain)

Minutes for RAG layer

Per-query cost

Embedding + LLM API

LLM API only

Embedding + fine-tuned LLM

Latency

Higher (retrieval adds 50 to 200ms)

Lower (no retrieval step)

Moderate

Source citation

Yes (native)

No (not possible)

Yes (via RAG)

Style consistency

Depends on prompt

High (baked in)

High (via fine-tuning)

Model swappability

High (RAG is model-agnostic)

Low (adapter tied to base)

Moderate (RAG swappable, adapter needs retraining)

Maintenance burden

Vector DB plus re-indexing

Training pipeline plus data curation

Both

Eval complexity

Retrieval metrics plus generation metrics

Task-specific metrics

Both


The key insight: RAG is cheaper to build and maintain, but caps at the quality of your retrieval. Fine-tuning is more expensive but locks in behavior. The hybrid gives you both at the cost of maintaining two systems.


Cost maintenance comparison table v3
Cost and maintenance comparison table visualization


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Common Mistakes and How to Avoid Them


Mistake 1: Fine-Tuning to Teach Facts


This is the most common and most expensive mistake. You fine-tune a model on your product documentation, and it works for a month. Then the documentation updates. The model now answers with stale information, and you have no way to fix it without retraining. Use RAG instead.


Mistake 2: Skipping the Re-Ranker


Plain vector similarity (cosine top-k) is the largest preventable quality cap in production RAG. A cross-encoder re-ranker over the top 20 to 50 candidates improves answer quality by 15 to 30% in most benchmarks. Use Cohere Rerank, BGE Reranker, or Voyage.


Mistake 3: Naive Fixed-Size Chunking


Splitting documents every 500 tokens regardless of structure shreds context. A chunk that cuts off mid-sentence loses meaning. Use semantic chunking that respects document structure: paragraphs, sections, or natural boundaries. Add 15% overlap between chunks to preserve context across boundaries.


Mistake 4: No Evaluation Harness


Without a labeled test set and automatic metrics, you cannot tell whether a change helped or regressed. Use Ragas, TruLens, or DeepEval. Measure retrieval quality (recall, precision) separately from generation quality (faithfulness, relevance). Set up evaluation in week one, not after launch.


Mistake 5: Full Fine-Tune When LoRA Would Do


Full fine-tunes are slower, more expensive, and harder to roll back than LoRA adapters. Start with LoRA. Move to full fine-tuning only if LoRA cannot reach the required quality after extensive hyperparameter tuning. In 2026, LoRA handles 90% of fine-tuning use cases.


Mistake 6: No Hybrid Retrieval


Vector-only search misses exact keyword matches. A product code, a person name, or a specific error message may not have a close vector neighbor but is an exact keyword match. Use hybrid retrieval (BM25 plus vector) to catch both semantic and lexical matches.


Common Mistakes and How to Avoid Them
Common Mistakes and How to Avoid Them: pedagogical overview


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Feynman Summary: Explain It Like You Are 12


Imagine you have a smart friend who has read every book in the library. That friend is the language model. Now you want your friend to answer questions about your school textbook.


RAG is like giving your friend the textbook and saying "look up the answer in here before you respond." Every time you ask a question, your friend opens the book, finds the right page, reads it, and gives you the answer. If the textbook gets updated, your friend automatically uses the new version because they check the book each time.


Fine-tuning is like sending your friend to a training camp where they learn to answer in a specific way: always use bullet points, always sound professional, always format the answer as a table. The training camp does not teach new facts. It teaches a style of answering.


Hybrid is doing both: your friend goes to the training camp to learn the style, and still checks the textbook for the facts. That gives you the best answers: correct facts, delivered in the right format.


The big mistake is sending your friend to training camp to memorize the textbook. They might remember some of it, but the moment the textbook changes, their memory is wrong, and you have to send them back to camp. Just let them check the book each time instead.



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Mindmap: The Complete Picture


Complete mindmap of RAG vs Fine-Tuning: When to Use Each
Complete mindmap of RAG vs Fine-Tuning: When to Use Each

This mindmap shows the full decision tree: start with the problem type (knowledge or behavior), follow the branch to the recommended approach (RAG, fine-tuning, or hybrid), and see the tools, costs, and trade-offs at each node.



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UNOP isochrone

UNOP Sound (University 365 Neuroscience Oriented Pedagogy)

Take five minutes to consolidate your memory. Play the isochronous tone track (10Hz alpha frequency) with your eyes closed. Alpha-frequency tones after a learning session support consolidation, helping move what you just learned from short-term to long-term memory.

[Audio player: UNOP Post-Lecture Isochrone (10Hz, 5 minutes)]


Practical Exercise: Build a Decision Matrix


Take a project you are working on (or imagine one) and walk through this decision matrix. Write your answers down.


Step 1: Define the Problem


Write one sentence describing what your LLM application needs to do. Example: "Answer customer support questions using our help center documentation."


Step 2: Answer These Questions


1. Does the knowledge change frequently (daily, weekly, monthly)? Yes or No.


2. Do you need to cite sources or show provenance? Yes or No.


3. Is your corpus larger than 200,000 tokens? Yes or No.


4. Does the model already produce correct facts but in the wrong format or tone? Yes or No.


5. Do you need a small, fast model for high-volume inference? Yes or No.


6. Do you have 500 or more curated input-output examples for fine-tuning? Yes or No.


Step 3: Apply the Decision Rules


- If you answered Yes to questions 1, 2, or 3: start with RAG.


- If you answered Yes to questions 4 or 5: consider fine-tuning.


- If you answered Yes to both groups: build the hybrid (RAG first, then fine-tune the residuals).


- If you answered No to everything: start with prompt engineering and revisit only when you hit a wall.


Step 4: Estimate Costs


- RAG build: 1 to 3 weeks of engineering time, plus embedding and vector database costs.


- Fine-tuning build: 4 to 8 weeks, including data preparation, GPU training, and evaluation.


- Hybrid: 6 to 12 weeks for the full system.


Write down your estimated timeline and budget. This exercise gives you a concrete starting point for your next LLM project discussion.



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Glossary


Term

Definition

RAG (Retrieval Augmented Generation)

Technique that retrieves relevant documents from an external index and passes them to the LLM as context at query time, without modifying model weights.

Fine-Tuning

Training process that adjusts model weights on a dataset of input-output examples to change the model behavior, style, or format.

LoRA (Low-Rank Adaptation)

Fine-tuning method that trains a small adapter module (under 1% of parameters) on top of a frozen base model. Cheap, fast, and reversible.

QLoRA

Extension of LoRA that quantizes the base model to 4-bit, reducing memory requirements enough to fine-tune large models on a single GPU.

DPO (Direct Preference Optimization)

Training method that fine-tunes models on preference pairs (output A is better than output B) without a separate reward model. Simpler than RLHF.

RLHF (Reinforcement Learning from Human Feedback)

Training method using a reward model and reinforcement learning to align model outputs with human preferences. Largely replaced by DPO in 2026.

Embedding

Vector representation of text that captures semantic meaning. Used to find similar passages by computing vector similarity.

Vector Database

Specialized database that stores and searches high-dimensional vectors. Examples: Pinecone, Weaviate, Qdrant, pgvector.

BM25

Sparse keyword matching algorithm that scores documents by term frequency and inverse document frequency. Used in hybrid retrieval alongside vector search.

Re-Ranker

Cross-encoder model that re-orders retrieved candidates by true relevance to the query. The biggest single quality lever in RAG pipelines.

Chunking

Process of splitting documents into smaller passages for embedding and retrieval. Semantic chunking respects document structure; naive chunking uses fixed token counts.

Hybrid Retrieval

Search approach combining dense vector similarity and sparse keyword matching (BM25) to catch both semantic and lexical matches.

Distillation

Fine-tuning a small model on outputs from a larger frontier model to achieve similar quality at lower cost. The strongest commercial case for fine-tuning in 2026.

Context Window

Maximum number of tokens a model can process in a single prompt. Frontier models in 2026 support up to 1M tokens.

Prompt Caching

API feature that caches static prompt prefixes at reduced cost (approximately 10% of normal input cost), making long-context strategies economically viable.

Agentic RAG

RAG pattern where the model decides when and what to retrieve, decomposes complex queries into sub-queries, and self-corrects when retrieved evidence is weak.

GraphRAG

RAG variant that combines knowledge graphs with vector search for entity-heavy, multi-hop reasoning queries.

Evaluation Harness

Automated testing framework that measures retrieval and generation quality on a labeled dataset. Examples: Ragas, TruLens, DeepEval.

Hallucination

Model output that is fluent and confident but factually incorrect. RAG reduces hallucinations by grounding answers in retrieved context.

UNOP

University 365 Neuroscience-Oriented Pedagogy: the teaching framework behind this lecture format, using brain-state preparation, microlearning, and spaced consolidation.



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Quiz: TEST YOUR UNDERSTANDING


1. Your company's product catalog changes weekly. You need a chatbot that answers questions about current products and prices. Which approach should you use first?


A) Fine-tune a model on the product catalog


B) Use RAG with the product catalog as the knowledge base


C) Use prompt engineering with the full catalog in the system prompt


D) Wait for the catalog to stabilize before building anything


2. What is the primary difference between RAG and fine-tuning?


A) RAG is faster to build, fine-tuning is more accurate


B) RAG changes what the model knows, fine-tuning changes how the model behaves


C) RAG uses GPUs, fine-tuning does not


D) RAG works with open-source models, fine-tuning works only with proprietary models


3. Which scenario is the strongest commercial case for fine-tuning in 2026?


A) Teaching a model your company's internal policies


B) Distilling frontier model performance into a smaller, cheaper model for a narrow task


C) Making the model aware of real-time stock prices


D) Building a customer support chatbot that cites sources


4. What is the most common mistake in RAG pipelines?


A) Using too many embeddings


B) Skipping the re-ranker step


C) Using a vector database instead of a relational database


D) Fine-tuning the embedding model


5. In the hybrid RAG plus fine-tuning pattern, what should you do first?


A) Fine-tune the model, then add RAG


B) Build RAG, identify behavioral failures, then fine-tune for those residuals


C) Fine-tune and build RAG simultaneously


D) Neither: use prompt engineering only



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Related Resources


U365 INSIDE Publications


- How LLMs Actually Work: Transformers in 20 Minutes (AI Foundations, Lecture 1)


- Vector Databases Explained: Embeddings for Search (AI Engineering, Lecture 4, coming soon)


- Prompt Engineering at Production Scale (AI Skills, Lecture 5, coming soon)


External Resources


- Attention Is All You Need (Vaswani et al., 2017): the original transformer paper


- LoRA: Low-Rank Adaptation of Large Language Models (Hu et al., 2021)


- Direct Preference Optimization (Rafailov et al., 2023)


- Ragas: evaluation framework for RAG pipelines


- Cohere Rerank documentation


- Qdrant, Weaviate, Pinecone, pgvector: vector database options


Related U365 Lectures (Coming Soon)


- Building Your First AI Agent with Function Calling (AI Agents, Lecture 3)


- Model Quantization: Running LLMs on Your Laptop (AI Engineering, Lecture 7)


- The AI Stack 2026: What Every Developer Needs (AI Engineering, Lecture 10)



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U.Copilot for This Lecture


Copy and paste this prompt into the U.Copilot AI Agent on university-365.com to explore this topic further:


I just completed the U365 INSIDE Lecture "RAG vs Fine-Tuning: When to Use Each" from UIT. I want to apply this to my own project. Help me: 1. Describe my use case in one sentence 2. Walk me through the decision matrix from the lecture 3. Recommend whether I should use RAG, fine-tuning, or a hybrid approach 4. Suggest specific tools and libraries for my recommended approach 5. Estimate the timeline and resources I will need My use case is: [describe your project here]



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Next Steps


1. Take the quiz above and check your answers at the bottom of this section.


2. Complete the Practical Exercise: build a decision matrix for a real or imagined project.


3. Read the next lecture in the AI Engineering series: Vector Databases Explained.


4. If you have not completed Lecture 1 (How LLMs Actually Work: Transformers in 20 Minutes), start there for the foundational architecture.


5. Visit university-365.com/uit to explore UIT programs in AI Engineering and Data Science.


6. Try the U.Copilot prompt above to get personalized recommendations for your project.


Answers: 1-B, 2-B, 3-B, 4-B, 5-B



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IMPORTANT NOTICE


Copyright University 365, Inc. All rights reserved.


This lecture is part of the U365 INSIDE Lectures series, produced by UIT (University 365 Institute of Technology) under the UDA Department of Academics. The content follows the UNOP (University 365 Neuroscience-Oriented Pedagogy) framework and the 5M2S (5 Minutes to Success) microlearning format.


All lectures in this series are free to access. For enrollment in UIT degree programs, certificate programs, or executive education, visit university-365.com/tuition.


For permissions or inquiries, contact uda@university-365.com.


This content is for educational purposes. Technical details about specific tools, pricing, and APIs reflect publicly available information as of September 2026 and may change. Always consult official documentation before making architecture decisions for production systems.



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Published by the Department of Academics, University 365.

Lecture delivered by the University 365 Institute of Technology (UIT).

Sam Utteker, Dean of Technology, UIT

Signed for the academic year 2026.

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